Rapid Exoproteome
Antigen Profiling (REAP)
is a discovery engine for functional autoantibody reactivities across the human exoproteome.
Exoproteome for biologically active reactivities
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Autoantibodies that target extracellular and secreted proteins (collectively, the “exoproteome”) exert potent biological effects that shape health and disease. Prior to REAP, these reactivities were difficult to detect accurately at scale.
By focusing on the exoproteome, REAP captures autoantibody reactivities most likely to exert direct biological effects.
By focusing on the exoproteome, REAP captures autoantibody reactivities most likely to exert direct biological effects.
Correctly folded proteins for sensitivity
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Genetic barcoding for scale
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